Cole Lab
Principal Investigator: Joanne Burnette Cole
Institution: University of Colorado Anschutz (Aurora, CO)
Primary Subfield: Genetics/Genomics
Recruitment Status: Inquire for rotation/fellowship opportunities
Research Focus
PROJECT ABSTRACT The Cole Lab’s overarching vision is to harness unique characteristics of the human genome to gain deeper insights into the impact of environmental risk factors on human disease. Our research focuses on two key areas. First, we aim to develop methods that address gaps in the derivation, analysis, and interpretation of phenotypes and their associations with markers of human health. Second, we utilize these and other approaches to identify risk factors and mechanisms related to disease, consequently driving the evolution of novel methods. These two pillars of my lab are synergistic, continually reinforce one another, and will support my lab’s sustainable growth. Over the next five years, our primary goals are to develop methods and expand resources for the broader scientific community that improve the derivation and utilization of environmental phenotypes for human disease research. One, we will improve the curation and optimization of phenotype pre-processing decisions using genetic heritability as an unbiased metric for phenotype precision. Two, we will use genetic correlation as a proxy for phenotypic correlation in non-overlapping individuals to evaluate phenotyp…
Active NIH Awards
- 5R35GM154792-03: Genetics as a tool to improve phenotypes and associations with human disease (2026)
- 5R00DK127196-05: Genetically harmonized dietary intake and causal relationships with diabetes-related outcomes (2025)
- 5R35GM154792-02: Genetics as a tool to improve phenotypes and associations with human disease (2025)
- 5R00DK127196-04: Genetically harmonized dietary intake and causal relationships with diabetes-related outcomes (2024)
- 1R35GM154792-01: Genetics as a tool to improve phenotypes and associations with human disease (2024)
Explore 700+ US Biology Labs on FindBioLabs.com