Liu Lab
Principal Investigator: Anli A Liu
Institution: New York University (New York, NY)
Primary Subfield: Neuroscience
Recruitment Status: ✅ Hiring Postdocs
Research Focus
PROJECT SUMMARY Episodic memories are representations of our personal past, anchored to time and space. Episodic memory impairments in neurological disorders like epilepsy, traumatic brain injury, and Alzheimer’s Disease significantly limit patients’ ability to work and live independently. In everyday life, the brain must process the continuous present to form discrete memories of the past. This ability to parse experience into meaningful chunks, termed event segmentation, is foundational to human episodic memory. Functional neuroimaging studies suggest that the hippocampus and a posterior cortical network demonstrate a simultaneous increase in activity at event boundaries and endings, but the neural events supporting this demarcation are unknown. Numerous rodent studies suggest that neural oscillations—particularly theta, gamma, and sharp-wave ripple (SWR) activity—coordinate hippocampal-neocortical interactions at these critical junctures. Our long-term goal is to discover how the brain organizes and consolidates continuous experience under naturalistic circumstances. The objective of this proposal is to measure the hippocampal-neocortical dynamics at key moments in episodic memo…
Active NIH Awards
- 5R01NS127954-04: Hippocampal-Neocortical Interactions During Naturalistic Learning (2026)
- 5R61DC022830-02: Human hippocampal oscillations during visuomotor exploration (2026)
- 5R01NS127954-03: Hippocampal-Neocortical Interactions During Naturalistic Learning (2025)
- 1R61DC022830-01: Human hippocampal oscillations during visuomotor exploration (2025)
- 5R01NS127954-02: Hippocampal-Neocortical Interactions During Naturalistic Learning (2024)
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