Blackmond Lab
Principal Investigator: Donna G Blackmond
Institution: Scripps Research Institute (La Jolla, CA)
Primary Subfield: Molecular & Cell Bio
Recruitment Status: ✅ Accepting PhD Students ✅ Hiring Postdocs
Research Focus
Project Summary/Abstract Over the past three decades, the Blackmond laboratory has pioneered research in kinetic-assisted mechanistic analysis of organic catalytic reactions. The data-rich methodology of Reaction Progress Kinetic Analysis (RPKA), employing in-situ reaction monitoring and kinetic modeling of temporal reaction profiles, has proven to be an innovative tool in organic synthesis and catalysis. Our work has helped to streamline pharmaceutical reaction process understanding as well as to provide fundamental mechanistic insights that contribute to catalyst design and development. Looking forward at the future landscape for research in synthetic organic chemistry, the significant potential for data-rich science focuses on artificial intelligence and machine learning (AI/ML) methods as an important theme in both academic and industrial research, fueling the promise of accelerated discovery. The experience and accomplishments of the Blackmond laboratory positions this group to make significant advances over the next five years in the study of complex catalytic networks, sometimes referred to as “systems chemistry.” Coupled catalytic cycles operating together may exhibit emergent b…
Active NIH Awards
- 5R35GM158320-02: Accelerating Discovery by Merging Kinetics with Data Science Methods in Catalytic Organic Reactions (2026)
- 1R35GM158320-01: Accelerating Discovery by Merging Kinetics with Data Science Methods in Catalytic Organic Reactions (2025)
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