Nievergelt Lab
Principal Investigator: Caroline M Nievergelt
Institution: University of California San Diego (La Jolla, CA)
Primary Subfield: Molecular & Cell Bio
Recruitment Status: ✅ Hiring Postdocs
Research Focus
Project Summary Psychiatric Genomics Consortium for PTSD Posttraumatic stress disorder (PTSD) occurs only in vulnerable individuals after exposure to severe traumatic events. This risk is due, in part, to 40-50% heritability of differential vulnerability. Due to increasing collaborations across the field of PTSD genomics and the advent of new analytical tools, it is a very exciting time for PTSD genetic risk discovery. The purpose of this application is to facilitate meta-analyses of genome- wide association study (GWAS) data for symptoms and diagnosis of PTSD. We propose to conduct large-scale meta-analyses through the PTSD group of the Psychiatric Genomics Consortium (PGC). The PGC was created in 2007 to conduct field-wide mega-analyses of individual data for 5 major psychiatric disorders. With its current 11 working groups, it is the largest consortium (>800 scientists from 40 countries) in the history of psychiatry. The PGC has produced major findings with regard to the genetic architecture of psychiatric disorders. The PGC-PTSD group was launched in 2013 and has been enormously successful. Currently our multi-ethnic data collection includes genotypes from 90 studies with a tot…
Active NIH Awards
- 5R01MH106595-11: Psychiatric Genomics Consortium for PTSD (2026)
- 5R01MH106595-10: Psychiatric Genomics Consortium for PTSD (2025)
- 2R01MH106595-09: Psychiatric Genomics Consortium for PTSD (2024)
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