Izard Lab
Principal Investigator: Tina Izard
Institution: University of Florida (Gainesville, FL)
Primary Subfield: Molecular & Cell Bio
Recruitment Status: ✅ Hiring Postdocs
Research Focus
Program Summary This Maximizing Investigators’ Research Award (MIRA) proposal is directly relevant to the long-range plans of the National Institute of General Medical Sciences (NIGMS). Our laboratory received continuous NIGMS funding since 2004 that allowed us to make substantial advances in our understanding of the mechanisms of the dynamic contacts between neighboring cells (adherens junctions), as well as between cells and the extracellular matrix (focal adhesions structures). These cell junctions, in addition of holding animal cells together, communicate signals and control the stress placed upon cells. Over the past 16 years, we contributed important mechanistic discoveries towards an understanding of · how the cell-cell junctions connect cells in tissues to regulate tissue homeostasis that are crucial to provide the tissue barrier of epithelia, as well as cell migration and proliferation; and · how cell junctions initiate and maintain cell adhesion while regulating the organization of the underlying actin cytoskeleton by establishing a center for cell signaling and gene transcript regulation. Such processes are highly dynamic and tightly regulated. Our laboratory focused on…
Active NIH Awards
- 5R35GM139604-06: Molecular Mechanisms of Cell Adhesion (2026)
- 3R35GM139604-06S1: Molecular Mechanisms of Cell Adhesion (2026)
- 5R35GM139604-05: Molecular Mechanisms of Cell Adhesion (2025)
- 3R35GM139604-04S1: Molecular Mechanisms of Cell Adhesion (2024)
- 5R35GM139604-04: Molecular Mechanisms of Cell Adhesion (2024)
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