Nair Lab
Principal Investigator: Veena A Nair
Institution: University of Wisconsin–Madison (Madison, WI)
Primary Subfield: Neuroscience
Recruitment Status: ✅ Hiring Postdocs
Research Focus
PROJECT SUMMARY Every year, more than 795,000 people in the United States have a stroke, with currently around 4.7 million survivors. Approximately 20% of survivors develop vascular contributions to cognitive impairments and dementia (VCID) which is second only to Alzheimer’s disease (AD). While several putative biomarkers are known, a considerable gap exists in stroke research in terms of validation and interaction of biomarkers of VCID. There is a critical need to better understand the complex interactions of VCID risk factors, baseline cognitive and brain health, and incident stroke lesion burden on post stroke brain changes and subsequent development of VCID. The specific aims of this project will address this need innovatively by (1) utilizing a novel neighborhood disadvantage atlas to geo-spatially map and quantify socio-economic disadvantage, (2) quantifying vascular risk burden, (3) incorporating baseline brain and cognitive health, (4) leveraging technical advances in state-of-the- art connectome MRI, and (5) applying network neuroscience and machine learning. In addition, we will recruit participants from underrepresented minority groups (African Americans, Hispanics, Nat…
Active NIH Awards
- 5R01NS123378-05: Stroke Connectome MRI Biomarkers for VCID Risk Assessment (2026)
- 5R01NS123378-04: Stroke Connectome MRI Biomarkers for VCID Risk Assessment (2025)
- 5R01NS123378-03: Stroke Connectome MRI Biomarkers for VCID Risk Assessment (2024)
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