Ryff Lab
Principal Investigator: Carol D. Ryff
Institution: University of Wisconsin–Madison (Madison, WI)
Primary Subfield: Neuroscience
Recruitment Status: Inquire for rotation/fellowship opportunities
Research Focus
ABSTRACT MIDUS has unprecedented opportunities to advance knowledge of risk and protective factors for cognitive decline as well as for Alzheimer’s Disease (AD) and Related Dementias (ADRD). Such potential stems from its comprehensive assessments from two national samples (Core, Refresher) of behavioral, social, psychological, and biological assessments from prior decades in the participants’ lives. Identifying markers of risk before disease symptomatology is foremost to AD/ADRD prevention science. Key aims are to: (1) Conduct additional waves of cognitive assessments on both national samples and obtain new measures focused on cognitive impairment. The Brief Test of Adult Cognition will be re-administered to ~ 4,000 adults (Core n = 2,062; Refresher n = 1,935), ages 25 to 95 at the last wave with key neuropsychological assessments of memory, speed, fluency, reasoning, and executive functioning. Global cognitive status will be assessed with the Telephone Interview for Cognitive Status and self-reported symptoms. (2) Conduct additional waves of emotion-related functional neuroimaging and psychophysiological assessments on Core and Refresher Neuroscience subsamples and obtain comprehe…
Active NIH Awards
- 5U01AG077928-05: Integrative Pathways to Cognitive, Affective, and Brain Health (2026)
- 5U19AG051426-10: Integrative Pathways to Health and Illness (2026)
- 5U19AG051426-10: Core A -- Administrative Core (2026)
- 5U19AG051426-10: Core C -- Statistics Core (2026)
- 5U19AG051426-10: Project 1 -- MIDUS Survey Project (2026)
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