Jadi Lab
Principal Investigator: Monika P. Jadi
Institution: Yale University (New Haven, CT)
Primary Subfield: Neuroscience
Recruitment Status: ✅ Accepting PhD Students ✅ Hiring Postdocs
Research Focus
Project Summary Active perception, the ability to seek out behaviorally relevant information, is guided by both cognitive and motor behaviors and is influenced by fluctuations in endogenous brain state. It is a result of the concerted activity of ensembles of neurons in the sensory hierarchy. These ensembles interact flexibly and dynamically as the organism transitions between various behavioral and brain states. However, the state-dependent information processing principles that underlie the activity of such ensembles are largely unknown. A rich body of theoretical and recent experimental work has shown that dependencies, such as co-variability, within an ensemble strongly influence their information carrying capacity and hence their functional efficacy. Further, theoretical investigation of these dependencies has revealed that their influence is determined by the extent of their alignment with the information coding dimension of an ensemble. The source of dependencies – shared vs. local – has been identified as a key determinant of this alignment. A critical step toward determining this source is to characterize the joint spiking activity (beyond pairwise correlations) of populat…
Active NIH Awards
- 5R01EY034605-04: Discovering brain state dependent dynamics in large scale perceptual ensembles. (2026)
- 5R01EY034605-03: Discovering brain state dependent dynamics in large scale perceptual ensembles. (2025)
- 5R01EY034605-02: Discovering brain state dependent dynamics in large scale perceptual ensembles. (2024)
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